Indication
Metflozin XR contains 2 prescription medicines called dapagliflozin and metformin HCl. Metflozin XR is used in adults with type 2 diabetes mellitus:
• to improve blood sugar (glucose) control along with diet and exercise.
• who have known cardiovascular disease or multiple cardiovascular risk factors and dapagliflozin is needed to reduce the risk of hospitalization for heart failure.
• who have heart failure (when the heart is weak and cannot pump enough blood to the rest of your body) and dapagliflozin is needed to reduce the risk of cardiovascular death and hospitalization for heart failure.
• to reduce the risk of further worsening of your kidney disease, end-stage kidney disease (ESKD), death due to cardiovascular disease, and hospitalization for heart failure in adults with chronic kidney disease.
Metflozin XR is not for people with type 1 diabetes. Metflozin XR may increase the risk of diabetic ketoacidosis (increased ketones in your blood or urine) in people with type 1 diabetes.
Metflozin XR is only for use in adults with type 2 diabetes mellitus, because it contains the prescription medicine metformin HCl.
Metflozin XR is not for use for treatment of chronic kidney disease in people with certain genetic forms of polycystic kidney disease, or who are taking or have recently received immunosuppressive therapy to treat kidney disease. If you have these conditions, Metflozin XR is not expected to work for treatment of chronic kidney disease.
It is not known if Metflozin XR is safe and effective in children younger than 18 years of age.
